Find 103041-38-9, Intermediate Of Dabigatran Etexilate Mesylate CAS 103041-38-9, CAS Number 103041-38-9 on Industry Directory, Reliable Manufacturer/Supplier/Factory from China.

Home > Products > Organic Amino Acid Powder > Cas 103041-38-9,3-(Pyridin-2-ylaMino)-Propionic Acid Ethyl Ester

Cas 103041-38-9,3-(Pyridin-2-ylaMino)-Propionic Acid Ethyl Ester

Cas 103041-38-9,3-(Pyridin-2-ylaMino)-Propionic Acid Ethyl Ester

    Payment Type: L/C,T/T
    Terms of Trade: FOB
    Min. Order: 1 Kilogram
    Delivery Time: 15 Days
    Packaging: AS REQUIRED
    Productivity: KGS
    Brand: VOLSENCHEM
    Transportation: Air
    Place of Origin: CHINA
    Supply Ability: 100KG
    Certificate: ISO

Basic Info

Model No.: 103041-38-9

Product Description

Dabigatran etexilate intermediate with the chemical name of 3-(Pyridin-2-ylaMino)-propionic acid ethyl ester CAS number 103041-38-9,Exactly speaking,it is the side chain of the intermediate of dabigatran etexilate in the fifth step. The appearance is off-white to white powder. Its usually produces the fifth step intermediate of dabigatran etexilate by reaction with 3-bromo-4- (methylamino) benzoic acid,details as follows: 34.4 g of 3-bromo-4- (methylamino),mixed with 240 mL of dichloromethane at room temperature and stirred for 1 hour and cooled to -20 ° C. 12.0 mL of thionyl chloride was added and then about 0.5 mL of N, N-dimethylformamide was added dropwise to continue the reaction for 4 hours. Until naturally rising to room temperature, then 29.12gram of ethyl 3- (pyridin-2-ylamino) propionate , 41.7ml were added, continued reaction for 6 hours at room temperature, the reaction was terminated by adding 300 mL of water, the organic layer was separated, The mixture was further washed with 200 mL of saturated aqueous sodium chloride solution, dried over anhydrous sodium sulfate and concentrated under reduced pressure to a total volume of about 100 mL. 50 mL of n-hexane was added to precipitate a solid which was stirred for 2.5 hours at room temperature. Vacumn Dried for 1 hour to give a white solid 57.7 g, this white solid was dabigatran etexilate intermediate N-5.

Thera. Category: Antithrombotic/Blood thinners

Cas No.:103041-38-9

Synonym:ethyl (2S)-2-[(pyridin-2-yl)aMino]propanoate;3-(Pyridin-2-ylaMino)-propionic acid ethyl ester;Ethyl 3-(2-PyridylaMino)propanoate;N-Ethyl 3-(pyridin-2-ylaMino)propanoate;N-[2]PYRIDYL-B-ALANIN-ETHYL ESTER;N-2-pyridinyl-β-Alanine,ethylester;ethyl 3-(pyridin-2-ylamino)propanoate;N-Pyridin-2-yl-beta-alanine ethyl ester;

103041-38-9

Molecular Weight:194.23036

Molecular formula:C10H14N2O2

Purity: ≥99.%

Appearance: White Crystalline solid

Packing:Export worthy packing

Material Safety Data Sheet:Available on request

Usage: It can treat and prevent blood clots, reducing the risk of stroke.

Related intermediate:

CAS
Chemical Name Specification Color
41263-74-5 4-(MethylaMino)-3-nitrobenzoic acid HPLC 99.0% pale brown
103041-38-9 N-[2]PYRIDYL-B-ALANIN-ETHYL ESTER HPLC 99.0% off white to white
429659-01-8 ETHYL N-[4-(METHYLAMINO)-3-NITROBENZOYL]-N-PYRIDIN-2-YL-SS-ALANINATE HPLC 99.0% orange yellow solid
42288-26-6
N-(4-CYANO-PHENYL)-GLYCINE HPLC 99.0% off white
Loss on drying 1.0%
212322-56-0
3-[(3-AMINO-4-METHYLAMINO-BENZOYL)-PYRIDIN-2-YL-AMINO]-PROPIONIC ACID ETHYL ESTER HPLC 99.0% off white
Melting point 101.0°C~106.0°C
Single impurity 0.3%
Loss on drying 0.5%
Residue on ignition 0.5%
Assay 98.0%
211915-84-3
Synonyms:3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino]propionic acid ethyl ester HPLC 99.0% off white
Single impurity 0.3%
Loss on drying 0.5%
Residue on ignition 0.5%
Assay 99.0%
872728-85-3 N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]arbonyl]-N-2-pyridinyl-beta-alanine ethyl ester 4-methylbenzenesulfonate HPLC 97.0% off white
211915-06-9
Dabigatran Etexilate HPLC 98.0% white
Single impurity 0.2%
Loss on drying 1.0%
Assay 98.0%
872728-81-9
Dabigatran etexilate mesylate HPLC 99.0% light yellow solid
Single impurity 0.5%
Loss on drying 1.0%
Residue on ignition 0.1%
Heavy melta 20 ppm
Assay 98.5%

 

Taizhou Volsen Chemical Co., Ltd. is professional in R&D, producing and marketing Pharmaceutical raw materials, pharmaceutical intermediates in China. VOLSEN consists of about 100 experienced employees including 3 PhD and 10 Master, and 35000 sqm facilities including research laboratories, kilo lab, pilot plant and full manufacturing plant,


VOLSEN R&D specialists, quality manager and sales with abundance experience make sure products are reliable and service is professional. The producing person inspect every step of the whole process and check up the quality strictly, in order to insure every batch of raw material achieve the standard of EP,CP, JP,BP etc.Matching to the diversified requirements of companies VOLSEN is steadily marching to reach the peaks.


Volsen owns a professional custom synthesis department, with more than 15 senior scientific research chemical personnels who have a graduate degree or above. We also have an independent scientific management system. Our company integrates years of production experiences and talent reserves that forms a strong R&D production capacity, furthermore we could undertake various chemicals customizations from kg to ton relying on the existing production base and equipment.


Manufacturing Unit is equipped with a facility of progressive reeducation of emissions, effluents and discharge of waste material that are known to have a negative impact on the environment. Besides, Laboratory as well as plant is equipped with latest Machinery, Equipments, Technical personnel & Means of communications.

Due to supply of reliable quality, efficient follow up, scheduled delivery and prompt response to any matter, company wins good comments from customers.

We aimed at delivering real business value to our clients. For any interest, pls call on us or email us to get our best services.

Company Info

  • Company Name: Taizhou Volsen Chemical Co., Ltd.
  • Representative: Mr Chen
  • Product/Service: Efinaconazole Intermediates , Isavuconazole Intermediates , Obeticholic Acid Intermediates , Vilanterol Intermediates , Dolutegravir Intermediates , Umeclidinium Bromide
  • Capital (Million US $): 60000000RMB
  • Year Established: 2002
  • Total Annual Sales Volume (Million US $): Above US$100 Million
  • Export Percentage: 91% - 100%
  • Total Annual Purchase Volume (Million US $): Below US$1 Million
  • No. of Production Lines: 5
  • No. of R&D Staff: 91 -100 People
  • No. of QC Staff: 11 -20 People
  • OEM Services Provided: yes
  • Factory Size (Sq.meters): 30,000-50,000 square meters
  • Factory Location: Dongying Economic Development Zone , Dongying, Shandong,China
  • Contact Person: Ms. Amy Cheng
  • Tel: 86-576-88869393
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